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Demethylating agents that belong to a group of nucleoside analogues all have cytosine-ring modifications that allow each compound to form a covalent complex with a DNA methyltransferase, thereby inhibiting further methylation

They play an intrinsic role in the physiological movements of water across cell membranes, and consequently through the entire organism 11,81

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support for attending meetings and/or travel from OMERACT, an international organization that develops measures for clinical trials and receives arms length funding from 12 pharmaceutical companies, as past steering committee member to attend their meeting every 2 years