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Impairment of the PINK1/Parkin pathway results in failure to clear damaged mitochondria in a timely manner, and these dysfunctional mitochondria become a sustained source of ROS, further exacerbating the lipid peroxidation burden (84)

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3.3 Causal impacts of exogenous antioxidant metabolites on osteoporosis risk Analogous conclusions emerged from our analysis of exogenous antioxidant metabolites (Figure 6), reinforcing the findings for their parent compounds