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Early surgical treatment does appear to show best short and long term results
Cancer cells exploit de novo GSH synthesis and glutathione peroxidase 4 (GPX4) activity to neutralize ROS [96]

doi: 10.1093/advances/nmab141 4 CowanSLimSAlyciaCPirottaSThomsonRGibson-HelmMet al

However, the toxic effect may occur in individuals who are unusually sensitive because of their genetics or their physical condition