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This leads to severe physical and biochemical damage, including lysosomal membrane permeabilization and subsequent lipid peroxidation, resulting in significantly improved tumor response in preclinical and clinical settings [194]

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Paraform sections were deparaffinized by sequential immersion in Xylene (I, II, III, #10023418, Sinopharm Chemical Reagent Co., Ltd, China) and graded alcohols (absolute ethanol I, II, 85%, and 75%) followed by washing in tap water