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& Stryer, L
While it is said that any organ can be affected by mitochondrial defects, the brain, skeletal muscle, and myocardium are most often affected because of their higher aerobic activity and higher mitochondrial content [181]

The concept that fatty acid synthesis is limited to the cytosol of lipogenic cells was recently revised

Eventually, foam cell formation modulates lipoprotein metabolism and causes lesions [83]
