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How the combined formulation may be evaluated Researchers may use a combined formulation to examine whether the compounds remain stable when stored together, how they behave within a fixed-volume delivery device and whether the blend presents any measurable formulation or handling differences compared with individual compounds

These chemicals can induce single-strand or double-strand DNA breaks as well which has been reported [78]

[9] Concomitant administration of large calcium supplements, thiazide diuretics, or aluminium-containing phosphate binders can potentiate vitamin D-mediated increases in serum calcium or phosphate, demanding periodic laboratory monitoring and dosage adjustments to avert nephrolithiasis or ectopic calcification

10.1186/1471-2148-8-39 BMC Evol