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In addition, TMAO induces several inflammatory pathways, which cause the activation of pro-inflammatory cytokines such as IL-6 and TNF- which causes chronic inflammation thereby causing plaque formation and plaque rupture leading to cardiovascular disease [71]

A simple theoretical model of GPLC and altered metabolic activity has been presented

Because its a perfect substitute for ground beef, you can swap in ground bison in nearly any favorite recipe you can come up with
