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Upon mitophagy, the pH of the mitochondria drops, changing the color of the mt-Kiema protein (102)

Noskovicova N, Schuster R, van Putten S, Ezzo M, Koehler A, Boo S, Coelho NM, Griggs D, Ruminski P, McCulloch CA, Hinz B

Deng Y, Chen D, Gao F, Lv H, Zhang G, Sun X, Miao Z (2019) Exosomes derived from microRNA-1385p-overexpressing bone marrow-derived mesenchymal stem cells confer neuroprotection to astrocytes following ischemic stroke via inhibition of LCN2

With a deeper understanding of ferroptosis during the occurrence and progression of cerebral I/R injury, new therapies to treat ischemic nerve damage by interfering with the molecular mechanism of ferroptosis are expected to be realized to some extent