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Description
Identification of a proton sensor that regulates conductance and open time of single hERG channels

Since CAT has a very rigid, stable structure, it is comparatively more resistant to changes in temperature, pH, and proteolysis, making it a unique antioxidant enzyme

Our findings, mirror the differences of Stage 2 or Stage 3 siblings when independently measured and show dramatic and statistically significant reductions of GPx3 in the most severely affect children ( p = 2.47 10 8 , Paired t-test) again with non-overlapping 95% confidence intervals (95% CI Unaffected Stage 2/3 [1.7 ug/ml, 2.1 ug/ml], 95% CI Konzo Stage 2/3 [0.98 ug/ml, 1.3 ug/ml]) (Fig

De Ita JR, Castilla-Cortzar I, Aguirre GA, Snchez-Yago C, Santos-Ruiz MO, Guerra-Menndez L, Martn-Estal I, Garca-Magario M, Lara-Daz VJ, Puche JE, Muoz U