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Before Reconstitution (Lyophilized Powder): The freeze-dried powder is quite stable

61st Annual Meeting Southern Thoracic Surgical Association:92, 2014

The MSM group reported less muscle soreness and joint pain than the placebo group ( Another study found that athletic men taking 3 grams of MSM daily for two weeks had lower levels of IL-6 and less muscle pain after intense resistance exercise (11)

Design issues include study objective, availability of data, sampling methods, data collection, cost of the design, time implications, controls, and ethical considerations (Wang and Kattan 2020)
