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Intracellular Ca 2+ concentration may affect PGC-1 expression either by activating CaMK and phosphorylating CREB, or via Calcineurin A and MEF-2

PMID 28515491

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In particular, 11 that play important role in the GTP-inhibition dynamics has contributed 84% for LRC formation in the closed form in contrast to its 33% inclusion in the open form (Table S6)
