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When exposed to ROS, Nrf2 migrates from the cytoplasm to the nucleus where it leads to the upregulation of expression of several antioxidant and detoxification genes (e.g., GSTs, SODs, and HO-1), the downregulation of NF-B, and reduction in proinflammatory cytokines (e.g., IL-6 and IL-1)

Not for clinical, therapeutic, or diagnostic use

Moreover, besides GzmB, limited information has been revealed regarding the endogenous inhibitors of Sb9 or the pathways regulated by Sb9

Stem cell treatment for PD may not be a good option for all cases, so we request that potential patients submit recent medical diagnoses, lab results/CT scans to our medical team for review