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70,71 Gerin et al established a septic lung injury model by cecum ligation and puncture in rats, showing that early administration of Quercetin reduced the levels of oxidative stress markers, such as xanthine oxidase (XO), nitric oxide (NO), and malondialdehyde (MDA), and increased the levels of antioxidant enzymes in lung tissues, leading to a reduction in oxidative stress and consequently reduced production of inflammatory factors in the lungs

Furthermore, we found that Sec24C overexpression elevated the expression of SLC7A11 at PM level, but the effect was abrogated upon exposure to Brefeldin A (Fig

Sambrotta M, Strautnieks S, Papouli E, Rushton P, Clark BE, Parry DA, Logan CV, et al

Obesity Obesity is a major risk factor for ED, involving multiple physiological processes including oxidative stress, inflammation, and endothelial dysfunction [147]