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Zhonghua Yi Xue Za Zhi 82: 941-944

Age-related NAD+ decline impairs this critical DNA repair pathway CD38 balance: The ectoenzyme CD38 consumes NAD+ and increases with age, creating a vicious cycle of NAD+ depletion and immune dysregulation By restoring NAD+ levels, supplementation recalibrates multiple aging pathways simultaneously: improved DNA repair, enhanced mitochondrial biogenesis, restored epigenetic regulation, activated autophagy, and improved nutrient sensing

doi:10.1016/S0968-0004(00)01712-6

investigated the effects of a probiotic mixture containing strains of Bifidobacterium and Lactobacillus on interleukin (IL)-10 levels in 33 patients with acne
