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When we have a clinical answer, we will make it available, with full transparency about what it does and does not do

The ankyrin-repeat inhibitory portion of unprocessed p100 therefore acts like a negative regulator by inhibiting DNA binding and nuclear localization of the NF-B heterodimer

Van Belleghem et al., 2007

Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson's disease
