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J Biol Chem 277:3212432132 Deng C, Sun Z, Tong G, Yi W, Ma L, Zhao B, Cheng L, Zhang J, Cao F, Yi D (2013) -Lipoic acid reduces infarct size and preserves cardiac function in rat myocardial ischemia/reperfusion injury through activation of PI3K/Akt/Nrf2 pathway

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Indeed, hypoxia contributes to high levels of oxidative stress [42], important in the context of depression, highlighted in this manuscript

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