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Biotechnol Bioprocess Eng 12:585593 Dorsam B, Fahrer J (2016) The disulfide compound alpha-lipoic acid and its derivatives: a novel class of anticancer agents targeting mitochondria

In addition, quality of life was significantly improved in the intervention group compared with the control group (Porcaro 2020)

However, due to low BBB penetration, it has been speculated that the mechanism of action of DS2 is not associated with modulatory effects on brain resident glial cells but rather through functional changes in peripheral immune cells (Jin et al., 2013