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Furthermore, since Se shortage reduces TXNRD activity, it compromises mitochondrial integrity [24]

ROS production occurs in multiple ways and is quite complex, however the oxidation of glutathione was pertinent when looking at fish species in which this AOP was based

10.1124/jpet.112.199497 J

Chauveau C, Rmy S, Royer PJ, Hill M, Tanguy-Royer SV, Hubert FO-X, et al