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[9] [10] Additionally, NAD+ is essential for the electron transport chain in mitochondria, the cellular powerhouses responsible for adenosine triphosphate (ATP) production

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Step 3: SAH in turn is converted to homocysteine by the enzyme S-adenosylhomocysteine hydrogenase (SAHH), which also produces adenosine

These procedures can result in a loss of cells that secrete intrinsic factor a protein in the stomach needed to absorb B12
