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The failure in bipolar depression treatment discovery is largely due to its complex pathophysiology with many known and unknown biological and environmental factors [4]
Structure and function of SET and MYND domain-containing proteins

P.Cys282Tyr homozygous females have a 1.3- to twofold increased risk of colorectal cancer, breast cancer, and arthritis compared to those without HFE gene pathogenic variants [25, 53]

doi: 10.1172/JCI72873
