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They are involved in different cellular processes such as DNA replication, sulfate assimilation or response to oxidative stress

So, they affect the structure, elasticity, and firmness of skin

B., RECOVER Mechanistic Pathways Task Force
SIRT1 deficiency in aging microglia contributes to aging- or tau-mediated memory deficits by upregulating IL-1 through promoter-specific hypomethylation (Cho et al., 2015)
