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Indeed, over-expression of arrestin 2 induces a selective uncoupling of DOR and KOR and reduces inhibition of ACase (Cheng et al., 1998)

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Best Pract Res Clin Endocrinol Metab (2019) 33:101290

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The field is evolving rapidly, and what was cutting-edge five years ago may be outdated by the time newer compounds complete their clinical programs

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