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A 2025 review found a small benefit from taking 400-1,200 IU per day, but a slightly older study from the National Institute for Health and Care Research showed it was only protective in people with vitamin D deficiency
doi: 10.1016/S0140-6736(13)62121-2
FUMA was used to annotate the genome-wide significant (GWS) risk loci ( p 0.0625) were identified, and one sample from each related pair was excluded 75
Diabetic rodents expressing DPP4 exhibit increased local activity of this protein at the cardiac level, which is associated with increased diastolic stiffness and relaxation time constant
