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& Kaufman, H

In this clinical trial, although participants did not undergo extended periods of fasting, 11.9 0.7% CR reduced LDL cholesterol, total: HDL cholesterol, and improved insulin sensitivity, independent of weight loss [79, 80]
The therapeutic cascade includes a significant upregulation of VEGF and TGF-, markers of angiogenesis and tissue remodelling, alongside an increase in IL-6, indicating an acute phase response

have reported a kojic acid analog namely 5-phenyl-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto]-4-(2,4-dihydroxylbenzylamino)-1,2,4-triazol as a potent competitive tyrosinase inhibitor with an IC 50 value of 1.35 2.15 M 412
