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Copper-Mediated Pathways: Research has explored its role as a copper-binding tripeptide in cellular signalling, antioxidant defence, and collagen-related biological models
For example, exposing endothelial cells to MOTS-c in vitro attenuated dysfunction caused by oxidative stress, in part by activating AMPK and suppressing inflammatory pathways (such as the MAPK/NF-B pathway) in those cells
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