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Under oxidative stress, excessive ROS emissions lead to mitochondrial damage, and loss or defects in mitochondrial energy production can enhance metabolic processes in the tricarboxylic acid (TCA) cycle, ETC, exacerbating ROS release and reducing antioxidant enzymes [81,82,83]

In breast cancer cell lines, resveratrol decreases the protein levels of arginine methyltransferase PRMT5, lysine methyltransferase EZH2, and lysine deacetylase KDAC in a dose- and time-dependent manner that correlated with an increase in protein levels of BRAC1, p21, and p53 genes

Over time, this leads to a brighter, more radiant complexion with reduced pigmentation