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While the relationship between zinc and COVID-19 has been extensively reviewed in the literature [408], this discussion will shift focus to other age-related diseases and the broader consequences of zinc deficiency, which is not only linked to immune dysfunction but also plays a significant role in other age-associated conditions, where immunological processes are not the sole contributors

In addition to an increase in inflammation levels, the number of tumor cells also increased in the number of tumor cells after GPX3 KO during the development of colitis-related cancers ( As mentioned earlier, the vast majority of GPX3 is secreted by the renal proximal convoluted tubules, so we speculate that the kidney may be a highly expressed organ of GPX3, and to test our hypothesis, we analyzed the GSE111159 dataset (This dataset mainly detects the gene sequencing of 10 tissues and organs of mouse kidney, liver, brain, lung, thymus, muscle, spleen, stomach, heart and testicle under physiological conditions to understand the gene expression of each tissue and organ) in the GEO database (Gene Expression Omnibus, We found that GPX3 had the highest level of expression in kidney tissue under mouse physiology (Figure 3A), which is consistent with the results of the analysis by Kim et al

References: Main article at: Human body diagrams Template location:Template:Human body diagrams The raster format) images below have most commonly used organs already included, and text and lines can be added in almost any graphics editor