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Safety and Efficacy of High-Dose Folinic Acid in Children with Autism: The Impact of Folate Metabolism Gene Polymorphisms

The longest MK-677 study to date lasted 24 weeks and was discontinued due to MK-677s potential to increase the rate of congestive heart failure (CHF) in elderly test subjects who had been recovering from hip fracture

10.1186/s12917-019-1850-8 70

Similarly, it does not exhibit features of traditional apoptosis, including cell shrinkage, chromatin condensation, apoptotic body formation, and cytoskeletal disintegration
