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The variety of receptors and molecules on their surfaceincluding pattern recognition receptors (PRRs), cytokine receptors, and chemokine receptorsplays a key role in controlling their differentiation, activation, and ability to engulf pathogens or debris (phagocytosis)

Emerging epigenetic evidencederived predominantly from experimental animal modelssuggests that prolonged or repeated exposure to supraphysiological doses of anabolicandrogenic steroids may induce persistent molecular alterations in the male reproductive system

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