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While B12 is generally safe, caution is needed in specific clinical situations: Lebers Disease (Hereditary Optic Neuropathy): B12 injections are generally contraindicated or should be used with extreme caution, as they may potentially aggravate optic atrophy in this rare condition

In longevity and metabolic studies, 5-Amino-1MQ stands out as a clean, versatile molecule backed by growing interest in NAD-based therapeutics

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