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Yao JK, Leonard S, Reddy R

In practical terms, some people notice symptoms after even a brief interruption

DOI:10.1001/jama.298.15.1763 122
Results showed that at 6 months, the methotrexate group experienced a significant reduction in average knee pain from a baseline of 6.4 to 5.1 on a numerical rating scale (NRS), compared to a decrease from 6.8 to 6.2 in the placebo group
