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Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor
In contrast, expression of GLRX, which promotes the conversion of active reduced glutathione (GSH) into its oxidized form (GSSG), was significantly decreased following melatonin treatment ( Figure 6G )

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Hyperphosphorylated tau bundles into intracellular neurofibrillary tangles, igniting widespread nerve-cell death throughout the hippocampus and cortex
