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Kim MP, Correa AM, Blackmon S, Quiroga-Garza G, Weilbaecher D, Bruckner B, Ramlawi B, Rice DC , Vaporciyan AA, Reardon MJ

Another study using the CIA mouse model also suggested that Clostridium cluster XIVa can activate transforming growth factor- (TGF-), thereby enhancing the immunosuppressive function of Tregs (125)

doi: 10.1016/j.carbpol.2016.03.002

This study suggests that airway microbiome dysbiosis not only serves as a key driver of chronic inflammation in COPD but may also be closely linked to the frequent occurrence of acute exacerbations ( From the lens of immune defense mechanisms, Richmond et al
