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Meanwhile, integrating the microbiome and transcriptome found that Bacteroidetes , Lachnospiracea incertaesedis and Clostridium XIVa were enriched in HCC patients, and their changes in the tumor immune microenvironment through serum bile acids may be important factors associated with liver cancer burden and poor clinical outcomes (93)

Chang WH, Tsai YS, Wang JY, Chen HL, Yang WH, Lee CC

Comments received after that date but by July 22, 2026, will be taken into consideration by FDA
