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This reduction in microbial diversity is consistent with observations in various other diseases such as non-alcoholic fatty liver disease, type 2 diabetes mellitus, hypertension and Alzheimers disease (1417)
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Mitochondria also harbor glucocorticoid receptors (GRs)that, upon activation, bind to the mitochondrial DNA glucocorticoid response element (GRE) sequence motif to regulate mitochondrial rRNA synthesis and gene expression [87, 88]
