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One thing that makes it unusual right off the bat: it's remarkably stable in stomach acid

doi: 10.1016/j.ceb.2015.04.016 5 DupontNJiangSPilliMOrnatowskiWBhattacharyaDDereticVet al

B 12 deficiency can also adversely affect the methylation reaction, increasing inflammatory responses [38], and reducing CD8+ and natural killer cell activity [39]
