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Is a higher dose always better

Gastroenterology 143 , 408417.e2 (2012)

The mice were killed (pentobarbital 100 mg/kg) at the conclusion of the study

Efficacy of roxithromycin in adult patients with rheumatoid arthritis who had not received disease-modifying antirheumatic drugs: a 3-month, randomized, double-blind, placebo-controlled trial