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By inhibiting NNMT, 5-Amino-1MQ increases cellular SAM and NAD+ levels, enhances NAD+ salvage pathway flux, activates SIRT-1, boosts oxidative phosphorylation (OXPHOS), and influences cellular energy homeostasis and epigenetic modifications

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Vitamin B12 deficiency often leads to nervous system damage that damages the optic nerve leading to your eyes

Individuals with gastrointestinal disorders that affect nutrient absorption, such as Crohns disease or celiac disease