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While results look promising, more human research is needed to confirm its long-term anti-aging effects

Due to the relatively low free energy change of the FH reaction, being around 0.8 kcal/mol (3.8kJ/mol) in the direction of malate production, the reaction is freely reversible

A similar study was conducted with 466 Danish patients with cirrhosis

(Folate deficiency disrupts normal DNA synthesis and methylation, which interferes with cell division and development, especially in rapidly dividing embryos.) Megaloblastic anemia, which can lead to symptoms like fatigue, weakness, and difficulty concentrating Elevated homocysteine, even when B12 levels are normal