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Menstrual Cycle Disorders as an Early Symptom of Energy Deficiency among Female Physique Athletes Assessed Using the Low Energy Availability in Females Questionnaire (LEAF-Q) PLoS ONE

Importantly, the proteomic similarity of Day 30 iHLOs to PHHs, with a 33.46% expression difference from liver tissue, underscores their physiological relevance compared to traditional models like HepG2 cells, which exhibit a 54.36% protein difference from liver tissue, or HepaRG cells, with a 45.40% protein difference

Guilherme A, Henriques F, Bedard AH, Czech MP

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