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At physiological or moderately elevated doses, pyridoxine is generally well tolerated, and side effects tend to be mild
It also improves tendon, ligament, and bone healing, accurately implementing its own angiogenic effect in the healing

RT-PCR An RNeasy kit (Qiagen, 74104) was used to extract total RNA from mice hippocampal tissue, and then the Transcriptor High Fidelity cDNA synthesis kit (Roche, 5081963001) was used to reverse transcribe the RNA into cDNA

Cold Spring Harbor perspectives in biology, 8(8), a005926
