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Weight loss with Tesofensine was primarily fat mass, with a notable preservation of lean mass as assessed by DEXA. Astrup et al., The Lancet May Improve Training Drive and Mood Elevated dopamine and norepinephrine levels can enhance motivation , focus , and mental resilience during challenging cutting phases

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In addition, several clinical trials have shown their potential in treating various disorders, including cognitive and behavioral disorders, narcolepsy, and other significant neurological disorders, such as AD and PD, that have been reviewed extensively elsewhere [16]
