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In addition, positive outcomes included lower blood pressure, decreased low-density lipoprotein (LDL)-cholesterol, and enhanced sensitivity to insulin
The A1ATD can be considered as a predisposing factor for the development of early and severe onset of FM in an individual with low A1AT serum levels (7% MZ, 0.5% SZ and 0.2% ZZ) (100)

There was also a trend toward higher concentrations of the osmolyte myo-inositol
