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Motor stimulation has also been described as a verification method in piriformis injection techniques, including ultrasound-based approaches and fluoroscopy/EMG-guided approaches

This is so because, due to a deficiency of iodine, the increased production of TSH stimulates compensatory growth of the thyroid follicular cells for the deficiency of these hormones, resulting in goiter (Kolesnik et al

However, these mainly utilised chemical assays, or at best UV-liquid chromatography quantification, to estimate tissue ET levels, methods which lack sensitivity and specificity 12