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Combination of FLT3 Inhibitor Quizartinib and MDM2 Inhibitor Milademetan Results in Greater Pre-Clinical Anti-Leukemic Activity in FLT3-ITD Mutant/P53 Wild-Type Acute Myeloid Leukemia Models
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19 , e7 (2017)
showed that transforming growth factor (TGF)- type II receptor knockout in mice gave rise to prostate and gut epithelial tumors by activating c-MET through paracrine overexpression of HGF by stromal cells [96]
