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Protection From Thyroid Disorders Given by Nutraceuticals Other Than the Omega-3 PUFA The very few studies available in the English-language literature on the omega-3 PUFA-based nutraceuticals in the clinical setting of autoimmune thyroid disorders (130, 131) ( Table 4 ) contrast with the large number of studies that have tested seleno-L-methionine alone (149151) or seleno-L-methionine combined with myo-inositol (151157), which is a hexahydroxycyclohexane (C 6 H 12 O 6 ) and one of the nine stereoisomers of inositol that plays a pivotal role in many metabolic pathways (158)

animal studies show embryotoxicity at supra-therapeutic doses, and human case reports describe placental passage, so use is justified only when potential benefit outweighs risk

Although higher dietary intake of certain nutrients (especially long-chain omega-3 fatty acids) and dietary factors (especially flavonoids) is associated with beneficial effects on cognitive function, it is unknown if micronutrient supplementation beyond the recommended dietary allowance (RDA) will benefit cognitive function in healthy individuals

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