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The liver handles roughly 90% of all ethanol metabolism through enzymatic oxidation

Although these three types of cells each have distinct functions, it is more important to note that the somatostatin, glucagon, and insulin they secrete work together through mutual regulation and feedback mechanisms to maintain blood glucose balance and overall metabolic homeostasis

Given its early involvement in the disease process, fornix pathology may be an early marker of disease rather than a consequence of chronicity