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Description
We anticipate insights from the ongoing phase I/II study of SCG101 (NCT05417932) will contribute to identifying a reliable biomarker for safe patient stratification

It has been reported that lung cancer cells exhibit upregulated expression of all key glycolytic enzymes [hexokinase 2 (HK2), phosphofructokinase and pyruvate kinase (PK)] (13), suggesting that the essential enzymes of the aerobic glycolytic pathway have a critical role in the development of lung carcinoma

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