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While not fully understood, the analgesic effects are believed to be due to the activation of the descending serotonergic inhibitory pathways in the central nervous system

We have previously shown that adenosine A1AR and A2AR of HSCs promote the activation and proliferation of HSCs after activation under the action of acetaldehyde

COX isoenzymes are also responsible for a peroxidase reaction, which is not affected by NSAIDs
