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Melena strongly suggests, and hematemesis confirms, that bleeding is of upper gastrointestinal originPeptic ulcer, the most common cause of gastrointestinal hemorrhage, should be pursued through questions about epigastric distress, the relationship of symptoms to food intake, and a history of peptic ulcer disease

Dietary Modifications Since the liver is already working overtime to process TMA, reducing other dietary sources of TMA can help lighten the load [6]

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